Many installations critical for military training and testing are located throughout the southeastern United States and provide essential habitat for numerous threatened, endangered, and at-risk species (TER-S). SERDP, ESTCP and the Legacy Resource Management Program sponsored a workshop to (1) assess TER-S management needs within a regional context, with an emphasis on system-level and cross-boundary approaches and to (2) identify potential partners and existing partnership structures, as well as gaps in knowledge, technology, management, and partnerships that, if addressed, could improve implementation of such approaches. During the course of the workshop, discussions resulted in the prioritization of investment opportunities to address such gaps and management challenges. These investment opportunities are described in the Workshop Proceedings.