This framework is intended to support site managers during the remedial decision-making process, including developing and evaluating remediation alternatives during a Remedial Investigation/Feasibility Study. By identifying current knowledge gaps, the methods will also directly support the refinement of conceptual site models and prove useful for risk assessments. Finally, as noted above, a key intended use for this framework is to aid regulators and other parties who manage portfolios of PFAS sites. In this case, the goal is to support the riskbased prioritization of PFAS sites to more effectively allocate resources for PFAS cleanup and management.